VARIANT LIBRARY3 DESIGNS
Choose a genetic implementation, then compile it into the event model.
FROM SPATIAL SPECIFICATION TO MICROBIAL IMPLEMENTATION
Translate enzyme geometry into sequence modules, expression events and a selectable microbial variant.
The first step releases an intermediate before the next enzyme can capture it. The design brings their addresses closer together.
Choose a genetic implementation, then compile it into the event model.
The compiler preserves addresses, ratios and approximate geometry. Transcription, translation, folding and recruitment are staged educational events, not atomistic trajectories.
THE TRANSLATION RULE
The design specification is compiled into RNA binding motifs, protein interaction domains and enzyme clients. The mapping is explicit so that each design choice can be inspected or mutated.